Stepwise evolution of the centriole-assembly pathway
نویسندگان
چکیده
منابع مشابه
Stepwise evolution of the centriole-assembly pathway.
The centriole and basal body (CBB) structure nucleates cilia and flagella, and is an essential component of the centrosome, underlying eukaryotic microtubule-based motility, cell division and polarity. In recent years, components of the CBB-assembly machinery have been identified, but little is known about their regulation and evolution. Given the diversity of cellular contexts encountered in e...
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t has been reported that nontransformed mammalian cells become arrested during G 1 in the absence of centrioles (Hinchcliffe, E., F. Miller, M. Cham, A. Khodjakov, and G. Sluder. 2001. Science . 291:1547–1550). Here, we show that removal of resident centrioles (by laser ablation or needle microsurgery) does not impede cell cycle progression in HeLa cells. HeLa cells born without centrosomes, la...
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It has been reported that nontransformed mammalian cells become arrested during G1 in the absence of centrioles (Hinchcliffe, E., F. Miller, M. Cham, A. Khodjakov, and G. Sluder. 2001. Science. 291:1547-1550). Here, we show that removal of resident centrioles (by laser ablation or needle microsurgery) does not impede cell cycle progression in HeLa cells. HeLa cells born without centrosomes, lat...
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15 صفحه اولCentriole Assembly: The Origin of Nine-ness
Recent studies of the Chlamydomonas bld10 mutant have revealed that the ninefold symmetry of the centriole is set by the length of the cartwheel spokes, which fixes the diameter, and thereby the circumference, of the centriole.
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2010
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.064931